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Article

The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish.

The Journal of biological chemistry - 30 Apr 2010

Verbruggen Vincianne, Ek Olivier, Georlette Daphné, Delporte François, Von Berg Virginie, Detry Nathalie, Biemar Frédéric, Coutinho Pedro, Martial Joseph A, Voz Marianne L, Manfroid Isabelle, Peers Bernard

Abstract excerpt

Pax6 is a well conserved transcription factor that contains two DNA-binding domains, a paired domain and a homeodomain, and plays a key role in the development of eye, brain, and pancreas in vertebrates. The recent identification of the zebrafish sunrise mutant, harboring a mutation in the pax6b...

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Source

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Identifiers

PMID: 20177065
DOI: 10.1074/jbc.M110.108019
PMCID: PMC2859549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20177065-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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