Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retrospective characterization of the S open reading frame of HBV isolated from children with membranous nephropathy treated with interferon-alpha2b.

Antiviral therapy - 1 Jan 2010

Gous Natasha, Bhimma Rajendra, Kew Michael, Kramvis Anna

Abstract excerpt

BACKGROUND: A causal relationship exists between HBV infection and membranous nephropathy. The association is especially close in Black children in sub-Saharan Africa. Interferon-alpha2b is commonly used to treat this condition, but is effective in only 30-40% of patients. The reason for the poor response is unknown. The objective of this study was to determine if mutations in the surface gene of HBV isolated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa South of the Sahara
Share to Glomerulonephritis, Membranous

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Protein Precursors

Share to Treatment Failure

Source

Identifiers

PMID: 20167992
DOI: 10.3851/IMP1487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retrospective characterization of the S open reading frame of HBV isolated from children with membranous nephropathy treated with interferon-alpha2b.PMID 20167992Read ↗

Study on hepatitis B virus pre-S/S gene mutations of renal tissues in children with hepatitis B virus-associated membranous nephropathy.Semantic proximity Read ↗

[Analysis of hepatitis B virus (HBV) preS1, preS2 and S gene regions from patient groups infected with HBV genotype D].Semantic proximity Read ↗

A Case of S-Variant Hepatitis B Virus: An Immune System Escape Artist.Semantic proximity Read ↗

Hepatitis B virus PreS/S gene variants: pathobiology and clinical implications.Semantic proximity Read ↗

Hepatitis B virus S gene mutants in infants infected despite immunoprophylaxis.Semantic proximity Read ↗

Sequence Variability of Hepatitis B Virus (HBV) Surface Antigen Gene (S Gene) Among the Non-responders of Antiviral TherapySemantic proximity Read ↗

Vaccination of chronic hepatitis B virus carriers with preS2/S envelope protein is not associated with the emergence of envelope escape mutants.Semantic proximity Read ↗

The hepatitis B virus seroconversion to anti-HBe is frequently associated with HBV genotype changes and selection of preS2-defective particles in chronically infected children.Semantic proximity Read ↗

Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels.Semantic proximity Read ↗

Divergent preS Sequences in Virion-Associated Hepatitis B Virus Genomes and Subviral HBV Surface Antigen Particles From HBV e Antigen-Negative Patients.Semantic proximity Read ↗

Analysis of the complete genome of subgroup A′ hepatitis B virus isolates from South AfricaSemantic proximity Read ↗

HBV PreS/S gene mutations in patients with chronic hepatitis B.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.