Article
Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.
The American journal of pathology - 1 Apr 2010
Mura Marco, Binnie Matthew, Han Bing, Li Chengjin, Andrade Cristiano F, Shiozaki Atsushi, Zhang Yu, Ferrara Napoleone, Hwang David, Waddell Thomas K, Keshavjee Shaf, Liu Mingyao
Abstract excerpt
Vascular endothelial growth factor-A (VEGF) is a potent regulator of vascular permeability, inflammatory response, and cell survival in the lung. To explore the functions of VEGF produced locally in type II pneumocytes, we generated mice with a conditional deletion of VEGF-A using Cre recombinase...
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