Article
Overexpression of interferon-activated gene 202 (Ifi202) correlates with the progression of autoimmune glomerulonephritis associated with the MRL chromosome 1.
Lupus - 1 Jul 2010
Ichii O, Kamikawa A, Otsuka S, Hashimoto Y, Sasaki N, Endoh D, Kon Y
Abstract excerpt
B6.MRLc1(82-100) congenic mice carrying the telomeric region of lupus-prone MRL chromosome 1 develop autoimmune glomerulonephritis (GN). The GN susceptibility locus of B6.MRLc1(82-100) contains the interferon activated gene 200 (Ifi200) family, which consists of Ifi202, 203, 204, and 205. Recentl...
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