Article
Supercoiling is essential for the formation and stability of the initiation complex at the divergent malEp and malKp promoters.
Journal of molecular biology - 5 Apr 1991
Richet E, Raibaud O
Abstract excerpt
malEp and malKp are divergent and partially overlapping promoters of the Escherichia coli maltose regulon, whose activity depends on the presence of two transcriptional activators. MalT and CRP (cAMP receptor protein). Their activation involves a common 210 base-pair regulatory region encompassin...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Carrier Proteins
- Cell-Free System
- Cyclic AMP Receptor Protein
- DNA, Bacterial
- DNA, Superhelical
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Kinetics
- Maltose
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic