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Article

Supercoiling is essential for the formation and stability of the initiation complex at the divergent malEp and malKp promoters.

Journal of molecular biology - 5 Apr 1991

Richet E, Raibaud O

Abstract excerpt

malEp and malKp are divergent and partially overlapping promoters of the Escherichia coli maltose regulon, whose activity depends on the presence of two transcriptional activators. MalT and CRP (cAMP receptor protein). Their activation involves a common 210 base-pair regulatory region encompassing multiple binding sites for both activators. Using a supercoiled plasmid containing malEp and malKp as template,...

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Identifiers

PMID: 2016744
DOI: 10.1016/0022-2836(91)90699-7

Genes

CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Supercoiling is essential for the formation and stability of the initiation complex at the divergent malEp and malKp promoters.PMID 2016744Read ↗

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Influence of DNA geometry on transcriptional activation in Escherichia coli.Semantic proximity Read ↗

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