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Article

Spectrum of activity, mutation rates, synergistic interactions, and the effects of pH and serum proteins for fusidic acid (CEM-102).

Diagnostic microbiology and infectious disease - 1 Mar 2010

Biedenbach Douglas J, Rhomberg Paul R, Mendes Rodrigo E, Jones Ronald N

Abstract excerpt

Fusidic acid (CEM-102) is a steroidal antimicrobial agent with focused Gram-positive activity that acts by preventing bacterial protein synthesis via interacting with elongation factor G. A collection of 114 wild-type isolates (> 80 species) was used to define the contemporary limits of fusidic a...

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PMID: 20159376
DOI: 10.1016/j.diagmicrobio.2009.10.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20159376-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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