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Article

GPR3 may not be a potential candidate gene for premature ovarian failure.

Reproductive biomedicine online - 1 Jan 2010

Zhou Sirui, Wang Binbin, Ni Feng, Wang Jing, Cao Yunxia, Ma Xu

Abstract excerpt

The G protein-coupled receptor gene GPR3 is expressed predominantly in oocytes, and functions in the early development of oocytes in the ovarian follicle. GPR3 is essential for meiotic arrest maintenance in mice, which makes it a candidate gene for premature ovarian failure (POF). The coding region of GPR3 was screened in 100 Chinese POF patients for variants of the GPR3 gene. Except for one novel variant in the...

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Source

Identifiers

PMID: 20158988
DOI: 10.1016/j.rbmo.2009.10.013

Genes

GPR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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