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Article

The circadian clock gene period extends healthspan in aging Drosophila melanogaster.

Aging - 19 Nov 2009

Krishnan Natraj, Kretzschmar Doris, Rakshit Kuntol, Chow Eileen, Giebultowicz Jadwiga M

Abstract excerpt

There is increasing evidence that aging is affected by biological (circadian) clocks - the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/night cycles. Recent data suggest that disruption of the mammalian circadian clock results in accelerated aging and increased age-related pathologies such as cancer; however, the links between loss of...

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Identifiers

PMID: 20157575
DOI: 10.18632/aging.100103
PMCID: PMC2815745

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