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Article

The CST3 BB genotype and low cystatin C cerebrospinal fluid levels are associated with dementia in Lewy body disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Maetzler Walter, Schmid Benjamin, Synofzik Matthis, Schulte Claudia, Riester Karin, Huber Heiko, Brockmann Kathrin, Gasser Thomas, Berg Daniela, Melms Arthur

Abstract excerpt

A large proportion of demented Lewy body disease patients have Alzheimer's disease (AD)- like pathology, in particular amyloid-beta (Abeta) plaques. Cystatin C (CysC) is a carrier of soluble Abeta (42) in the cerebrospinal fluid (CSF) and reduces Abeta plaque formation. The CST3 BB genotype leads...

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Source

Identifiers

PMID: 20157249
DOI: 10.3233/JAD-2010-1289

Genes

CST3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20157249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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