Article
Reproductive fitness advantage of BCR-ABL expressing leukemia cells.
Cancer letters - 1 Aug 2010
Traulsen Arne, Pacheco Jorge M, Dingli David
Abstract excerpt
Mutations in oncogenes and tumor suppressor genes confer a fitness advantage to cells that can lead to cancer. The tumor phenotype normally results from the interaction of many mutant genes making it difficult to estimate the fitness advantage provided by any oncogene, except when tumors depend o...
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