Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.

The Journal of biological chemistry - 17 Mar 2006

Kim Eun A, Noh Yoon Tae, Ryu Myung-Jeom, Kim Hyun-Taek, Lee Sung-Eun, Kim Cheol-Hee, Lee Cheolju, Kim Young Ho, Choi Cheol Yong

Abstract excerpt

Pax6 is a transcriptional activator that contains two DNA binding domains and a potent transcription activation domain in the C terminus, which regulates organogenesis of the eye, nose, pancreas, and central nervous system. Homeodomain-interacting protein kinase 2 (HIPK2) interacts with transcription factors, including homeoproteins, and regulates activities of transcription factors. Here we show that HIPK2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glucagon
Share to Glutamic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luciferases

Share to p300-CBP Transcription Factors

Share to Paired Box Transcription Factors

Share to PAX6 Transcription Factor

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Threonine

Source

Identifiers

PMID: 16407227
DOI: 10.1074/jbc.M507227200

Genes

HIPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.PMID 16407227Read ↗

HIPK2 in the physiology of nervous system and its implications in neurological disordersSemantic proximity Read ↗

Signaling pathways of PAX2 and its role in renal interstitial fibrosis and glomerulosclerosis.Semantic proximity Read ↗

Posttranslational modifications regulate HIPK2, a driver of proliferative diseasesSemantic proximity Read ↗

Integration of stress signals by homeodomain interacting protein kinasesSemantic proximity Read ↗

STAT3 Protein–Protein Interaction Analysis Finds P300 as a Regulator of STAT3 and Histone 3 Lysine 27 Acetylation in PericytesSemantic proximity Read ↗

Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitorsSemantic proximity Read ↗

MYPT1/PP1‐Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial–Mesenchymal Transition in Fibrosis through Control of Multiple Families of GenesSemantic proximity Read ↗

Computational Prediction and Experimental Verification of New MAP Kinase Docking Sites and Substrates Including Gli Transcription FactorsSemantic proximity Read ↗

The Sweet Side of HIPK2Semantic proximity Read ↗

Homeodomain-Interacting Protein Kinase 1 Modulates Daxx Localization, Phosphorylation, and Transcriptional ActivitySemantic proximity Read ↗

Pin1 is required for the Ser727 phosphorylation-dependent Stat3 activitySemantic proximity Read ↗

Homeodomain-interacting protein kinase HIPK4 regulates phosphorylation of manchette protein RIMBP3 during spermiogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.