Article
Variation and molecular evolution of HmbR, the Neisseria meningitidis haemoglobin receptor.
Microbiology (Reading, England) - 1 May 2010
Evans Nicholas J, Harrison Odile B, Clow Kirsten, Derrick Jeremy P, Feavers Ian M, Maiden Martin C J
Abstract excerpt
Meningococcal disease caused by serogroup B Neisseria meningitidis remains an important health problem in many parts of the world, and there are currently no comprehensive vaccines. Poor immunogenicity, combined with immunological identity to human sialic acids, have hindered the development of a serogroup B conjugate vaccine, resulting in the development of alternative vaccine candidates, including many...
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