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Article

TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status.

Journal of translational medicine - 10 Feb 2010

Herreros-Villanueva Marta, Muñiz Pilar, García-Girón Carlos, Cavia-Saiz Mónica, del Corral María J Coma

Abstract excerpt

BACKGROUND: Although there have been many studies on the p73 gene, some of its functions still remain unclear. There is little research on the relationship between p73 gene transcription and its protein expression and the response to certain drugs such as oxaliplatin and cetuximab, which are drugs currently used in colorectal cancer.The purpose of this study was to evaluate the impact of TAp73 expression on...

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Share to Oxaliplatin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal, Humanized

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 20146801
DOI: 10.1186/1479-5876-8-15
PMCID: PMC2841128

Provenance

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