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Article

Blastocyst biopsy and vitrification are effective for preimplantation genetic diagnosis of monogenic diseases.

Human reproduction (Oxford, England) - 1 May 2013

Chang Li-Jung, Huang Chu-Chun, Tsai Yi-Yi, Hung Chia-Cheng, Fang Mei-Ya, Lin Yi-Chun, Su Yi-Ning, Chen Shee-Uan, Yang Yu-Shih

Abstract excerpt

STUDY QUESTION: What is the value of a new strategy for preimplantation genetic diagnosis (PGD) of monogenic diseases: blastocyst biopsy, cryopreservation and thawed embryo transfer? SUMMARY ANSWER: This strategy is highly effective for PGD of monogenic diseases and merits wide use. WHAT IS KNOWN ALREADY: PGD of monogenic diseases is conventionally performed on 6- to 8-cell embryos with fresh transfer. The...

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Identifiers

PMID: 23482337
DOI: 10.1093/humrep/det048

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PGD
ADO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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