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Article

Alzheimer disease-like phenotype associated with the c.154delA mutation in progranulin.

Archives of neurology - 1 Feb 2010

Kelley Brendan J, Haidar Wael, Boeve Bradley F, Baker Matt, Shiung Maria, Knopman David S, Rademakers Rosa, Hutton Mike, Adamson Jennifer, Kuntz Karen M, Dickson Dennis W, Parisi Joseph E, Smith Glenn E, Petersen Ronald C

Abstract excerpt

OBJECTIVE: To characterize a kindred with a familial neurodegenerative disorder associated with a mutation in progranulin (PGRN), with emphasis on the unique clinical features in this kindred. DESIGN: Antemortem and postmortem characterization of a kindred with a familial neurodegenerative disorder. SETTING: Multispecialty group academic medical center. PATIENTS: Affected members of a kindred with dementia with...

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Identifiers

PMID: 20142525
DOI: 10.1001/archneurol.2010.113
PMCID: PMC2902004

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Source receipt: pubmed, retrieved 7 Sept 2026.

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