Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iodine induces apoptosis via regulating MAPKs-related p53, p21, and Bcl-xL in thyroid cancer cells.

Molecular and cellular endocrinology - 14 May 2010

Liu Xiao Hong, Chen George G, Vlantis Alexander C, Tse Gary M, van Hasselt C Andrew

Abstract excerpt

Thyroid cancer is the most common endocrine malignancy and exhibits the full range of malignant behaviors from the relatively indolent occult differentiated thyroid cancer to uniformly aggressive and lethal anaplastic thyroid cancer. Iodine is a well known key element in thyroid normal function m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to bcl-X Protein
Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Cytoprotection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Activation

Share to Iodine

Share to MAP Kinase Signaling System

Share to Mitogen-Activated Protein Kinases

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 20138958
DOI: 10.1016/j.mce.2010.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20138958-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iodine induces apoptosis via regulating MAPKs-related p53, p21, and Bcl-xL in thyroid cancer cells.PMID 20138958Read ↗

Excessive Iodine Induces Thyroid Follicular Epithelial Cells Apoptosis by Activating HIF-1α-mediated Hypoxia Pathway in Hashimoto ThyroiditisSemantic proximity Read ↗

[Genetic alterations in MAPK and PI3K/Akt signaling pathways and the generation, progression, diagnosis and therapy of thyroid cancer].Semantic proximity Read ↗

Apoptosis: life through planned cellular death regulating mechanisms, control systems, and relations with thyroid diseases.Semantic proximity Read ↗

PI3K/Akt/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma.Semantic proximity Read ↗

NVP-BEZ235 inhibits thyroid cancer growth by p53- dependent/independent p21 upregulationSemantic proximity Read ↗

Thyroid Hormone, Cancer, and ApoptosisSemantic proximity Read ↗

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathwaySemantic proximity Read ↗

ANTP-SmacN7 Enhances Radiosensitivity in TPC-1 Cells Through XIAP-Mediated Activation of Apoptotic ProteinSemantic proximity Read ↗

CircTP53 promotes the proliferation of thyroid cancer via targeting miR-1233-3p/MDM2 axisSemantic proximity Read ↗

Induction of Cancer Cell Death by Isoflavone: The Role of Multiple Signaling PathwaysSemantic proximity Read ↗

Effect of iodine on early stage thyroid autonomy.Semantic proximity Read ↗

Effects of boric acid on proliferation, apoptosis and miRNAs in medullary thyroid cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.