Article
HES1 and HES5 are dispensable for cartilage and endochondral bone formation.
Cells, tissues, organs - 1 Jan 2010
Karlsson C, Brantsing C, Kageyama R, Lindahl A
Abstract excerpt
Notch signalling, via its downstream mediators HES1 and HES5, regulates development of several different tissues. In vitro studies suggest that these genes are also involved in chondrogenesis and endochondral bone formation. In order to investigate the importance of HES1 and HES5 for these develo...
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