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Article

Dynamic evolution of Mhc haplotypes in cynomolgus macaques of different geographic origins.

Immunogenetics - 1 Aug 2022

de Groot Natasja G, de Groot Nanine, de Vos-Rouweler Annemiek J M, Louwerse Annet, Bruijnesteijn Jesse, Bontrop Ronald E

Abstract excerpt

The major histocompatibility complex (MHC) plays a key role in immune defense, and the Mhc genes of cynomolgus macaque display a high degree of polymorphism. Based on their geographic distribution, different populations of cynomolgus macaques are recognized. Here we present the characterization of the Mhc class I and II repertoire of a large pedigreed group of cynomolgus macaques originating from the mainland...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35084546
DOI: 10.1007/s00251-021-01249-y
PMCID: PMC8792142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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