Article
A quick and robust MHC typing method for free-ranging and captive primate species.
Immunogenetics - 1 Apr 2017
de Groot N, Stanbury K, de Vos-Rouweler A J M, de Groot N G, Poirier N, Blancho G, de Luna C, Doxiadis G G M, Bontrop R E
Abstract excerpt
Gene products of the major histocompatibility complex (MHC) of human and non-human primates play a crucial role in adaptive immunity, and most of the relevant genes not only show a high degree of variability (polymorphism) but also copy number variation (CNV) is observed. Due to this diversity, MHC proteins influence the capability of individuals to cope with various pathogens. MHC and/or MHC-linked gene products...
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