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Mechanical Signals, IGF-I Gene Splicing, and Muscle Adaptation

15 Jul 2005

Abstract excerpt

Combining physiological and molecular biology methods made it possible to identify and characterize a local muscle growth/repair factor (MGF). Following resistance exercise, MGF "kick starts" muscle hypertrophy and is important in local tissue repair. Loss of muscle mass in old age and certain diseases is associated with an impaired ability to express MGF.

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Identifiers

PMID: 16024511
DOI: 10.1152/physiol.00004.2005

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