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Article

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise

1 Feb 2003

Abstract excerpt

The mRNA expression of two splice variants of the insulin-like growth factor-I (IGF-I) gene, IGF-IEa and mechano growth factor (MGF), were studied in human skeletal muscle. Subjects (eight young, aged 25-36 years, and seven elderly, aged 70-82 years) completed 10 sets of six repetitions of single legged knee extensor exercise at 80 % of their one repetition maximum. Muscle biopsy samples were obtained from the...

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PMID: 12562960
DOI: 10.1111/j.1469-7793.2003.00247.x

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