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Article

IDH1 mutations in gliomas: when an enzyme loses its grip.

Cancer cell - 19 Jan 2010

Frezza Christian, Tennant Daniel A, Gottlieb Eyal

Abstract excerpt

The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studying isocitrate dehydrogenase (IDH) mutations since their discovery just over a year ago. In a recent study published in Nature, Dang et al. identified 2-hydroxyglutarate as a product of tumor-associa...

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Source

Identifiers

PMID: 20129244
DOI: 10.1016/j.ccr.2009.12.031

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20129244-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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