Article
Population-based differences in treatment outcome following anticancer drug therapies.
The Lancet. Oncology - 1 Jan 2010
Ma Brigette By, Hui Edwin P, Mok Tony Sk
Abstract excerpt
Population-based differences in toxicity and clinical outcome following treatment with anticancer drugs have an important effect on oncology practice and drug development. These differences arise from complex interactions between biological and environmental factors, which include genetic diversity affecting drug metabolism and the expression of drug targets, variations in tumour biology and host physiology,...
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