Article
The role of pharmacoethnicity in the development of cytotoxic and molecular targeted drugs in oncology.
Yonsei medical journal - 1 Jan 2013
Saijo Nagahiro
Abstract excerpt
The effective and toxic ranges of anticancer drugs are very narrow and, in some cases, inverted. Thus determination of the most appropriate dosage and schedule of administration is crucial for optimal chemotherapy. In common arm trials conducted in Japan and by Southwest Oncology Group (SWOG) that used the same doses and schedules for the administration of carboplatin plus paclitaxel, the frequency of...
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