Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.

Cancer research - 15 Feb 2010

Slattery Martha L, Herrick Jennifer, Curtin Karen, Samowitz Wade, Wolff Roger K, Caan Bette J, Duggan David, Potter John D, Peters Ulrike

Abstract excerpt

Genome-wide association studies (GWAS) have identified SMAD7 on 8q21 as being associated with colorectal cancer. We evaluated single nucleotide polymorphisms (SNP) in the SMAD7 gene, including rs4939827, rs12953717, and rs4464148, previously identified from GWAS in a large population-based case-c...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carcinoma
Share to Case-Control Studies
Share to Colonic Neoplasms
Share to Gene Frequency
Share to Polymorphism, Single Nucleotide
Share to Risk Factors
Share to Smad7 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 20124488
DOI: 10.1158/0008-5472.CAN-08-1792
PMCID: PMC2925533

Genes

SMAD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20124488-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.PMID 20124488Read ↗

Association of common genetic variants in SMAD7 and risk of colon cancer.Semantic proximity Read ↗

Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry.Semantic proximity Read ↗

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.Semantic proximity Read ↗

SMAD7 rs4939827 variant contributes to colorectal cancer risk in Chinese population.Semantic proximity Read ↗

Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case-control studies.Semantic proximity Read ↗

A common SMAD7 variant is associated with risk of colorectal cancer: evidence from a case-control study and a meta-analysis.Semantic proximity Read ↗

SMAD7 gene polymorphisms and their influence on patients with colorectal cancer.Semantic proximity Read ↗

Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk.Semantic proximity Read ↗

Colorectal Cancer Risk Prediction Using the rs4939827 Polymorphism of the SMAD7 Gene in the Romanian PopulationSemantic proximity Read ↗

A risk-associated single nucleotide polymorphism of SMAD7 is common to colorectal, gastric, and lung cancers in a Han Chinese population.Semantic proximity Read ↗

Intronic polymorphisms of the SMAD7 gene in association with colorectal cancer.Semantic proximity Read ↗

Correlation Between CASC8, SMAD7 Polymorphisms and the Susceptibility to Colorectal Cancer: An Updated Meta-Analysis Based on GWAS Results.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.