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Article

Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo.

Molecular cancer therapeutics - 1 Feb 2010

Xu Tong, Xu Yucheng, Liao Chun-Peng, Lau Roy, Goldkorn Amir

Abstract excerpt

Telomerase plays a critical role in cancer, prompting the pursuit of various telomerase-based therapeutic strategies. One such strategy, telomerase interference, exploits the high telomerase activity in cancer cells and reprograms telomerase to encode "toxic" telomeres. To date, telomerase interf...

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Identifiers

PMID: 20124445
DOI: 10.1158/1535-7163.MCT-09-0682
PMCID: PMC2820598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20124445-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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