Article
A new strategy for genome assembly using short sequence reads and reduced representation libraries.
Genome research - 1 Feb 2010
Young Andrew L, Abaan Hatice Ozel, Zerbino Daniel, Mullikin James C, Birney Ewan, Margulies Elliott H
Abstract excerpt
We have developed a novel approach for using massively parallel short-read sequencing to generate fast and inexpensive de novo genomic assemblies comparable to those generated by capillary-based methods. The ultrashort (<100 base) sequences generated by this technology pose specific biological an...
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