Article
Cystic fibrosis transmembrane conductance regulator gene mutation and lung cancer risk.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2010
Li Yafei, Sun Zhifu, Wu Yanhong, Babovic-Vuksanovic Dusica, Li Yan, Cunningham Julie M, Pankratz Vernon S, Yang Ping
Abstract excerpt
The cystic fibrosis transmembrane conductance regulator (CFTR) holds an important role in retaining lung function, but its association with lung cancer is unclear. A case-control study was conducted to determine the possible associations of the genetic variants in the CFTR gene with lung cancer risk. Genotypes of the most common deletion DeltaF508, one functional SNP, and eight tag SNPs in the CFTR gene were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
