Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter hypermethylation of the CFTR gene and clinical/pathological features associated with non‐small cell lung cancer

17 May 2011

Abstract excerpt

BACKGROUND AND OBJECTIVE: The exact role of the cystic fibrosis transmembrane conductance regulator (CFTR) in pathophysiology, and the mechanisms regulating its expression are poorly understood. The CFTR gene is known to be genetically or epigenetically associated with several cancers. In the present study, the methylation status of the promoter region of the CFTR gene and its expression in primary non-small cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Cystic Fibrosis Research Advances
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21585618
DOI: 10.1111/j.1440-1843.2011.01994.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Promoter hypermethylation of the CFTR gene and clinical/pathological features associated with non‐small cell lung cancerPMID 21585618Read ↗

Exploring the methylation status of CFTR and PKIA genes as potential biomarkers for lung adenocarcinomaSemantic proximity Read ↗

Epigenetics in Cystic Fibrosis: Epigenetic Targeting of a Genetic Disease.Semantic proximity Read ↗

Cystic fibrosis transmembrane conductance regulator gene mutation and lung cancer risk.Semantic proximity Read ↗

DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcriptionSemantic proximity Read ↗

Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cellsSemantic proximity Read ↗

DNA polymorphisms in potential regulatory elements of the CFTR gene alter transcription factor binding.Semantic proximity Read ↗

CFTR and Gastrointestinal Cancers: An UpdateSemantic proximity Read ↗

DNA methylation in pulmonary fibrosis and lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.