Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of the Chd6 exon 12 affects motor coordination.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2010

Lathrop Melissa J, Chakrabarti Lisa, Eng Jeremiah, Rhodes C Harker, Lutz Thomas, Nieto Amelia, Liggitt H Denny, Warner Sandra, Fields Jennifer, Stöger Reinhard, Fiering Steven

Abstract excerpt

Members of the CHD protein family play key roles in gene regulation through ATP-dependent chromatin remodeling. This is facilitated by chromodomains that bind histone tails, and by the SWI2/SNF2-like ATPase/helicase domain that remodels chromatin by moving histones. Chd6 is ubiquitously expressed in both mouse and human, with the highest levels of expression in the brain. The Chd6 gene contains 37 exons, of which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to DNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Motor Activity

Share to NF-E2-Related Factor 2

Share to Postural Balance

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 20111866
DOI: 10.1007/s00335-010-9248-8
PMCID: PMC2844962

Genes

CHD6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of the Chd6 exon 12 affects motor coordination.PMID 20111866Read ↗

The Mechanisms of CHD8 in Neurodevelopment and Autism Spectrum Disorders.Semantic proximity Read ↗

The Chd family of chromatin remodelers.Semantic proximity Read ↗

A review of 18p deletions.Semantic proximity Read ↗

Versatile Roles of the Chromatin Remodeler CHD7 during Brain Development and DiseaseSemantic proximity Read ↗

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.Semantic proximity Read ↗

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.Semantic proximity Read ↗

Alterations in background ECoG activity and behavioral deficits in a mouse model of CHD2-related developmental delaySemantic proximity Read ↗

Adult-onset dystonia associated with CHD8 truncating variants: case series and targeted literature review.Semantic proximity Read ↗

Ccndbp1 is a new positive regulator of skeletal myogenesis.Semantic proximity Read ↗

Clinically relevant mouse models of severe spinal muscular atrophy with respiratory distress type 1.Semantic proximity Read ↗

Behavioral and epileptic phenotypes in a CHD2-related developmental delay model.Semantic proximity Read ↗

A 1.1Mb deletion in distal 13q deletion syndrome region with congenital heart defect and postaxial polydactyly: additional support for a CHD locus at distal 13q34 region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.