Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-221 suppresses ICAM-1 translation and regulates interferon-gamma-induced ICAM-1 expression in human cholangiocytes.

American journal of physiology. Gastrointestinal and liver physiology - 1 Apr 2010

Hu Guoku, Gong Ai-Yu, Liu Jun, Zhou Rui, Deng Caishu, Chen Xian-Ming

Abstract excerpt

Aberrant cholangiocyte reactions in response to inflammatory stimuli are important pathogenic factors for the persistent biliary inflammation in patients with cholangiopathies. Overexpression of intercellular cell adhesion molecule-1 (ICAM-1) in cholangiocytes is a common pathological feature in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Bile Ducts
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dactinomycin

Share to Intercellular Adhesion Molecule-1

Share to Interferon-gamma

Share to Jurkat Cells

Share to STAT1 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 20110463
DOI: 10.1152/ajpgi.00490.2009
PMCID: PMC2853302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20110463-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

miR-221 suppresses ICAM-1 translation and regulates interferon-gamma-induced ICAM-1 expression in human cholangiocytes.PMID 20110463Read ↗

MicroRNA-513 Regulates B7-H1 Translation and Is Involved in IFN-γ-Induced B7-H1 Expression in CholangiocytesSemantic proximity Read ↗

HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1Semantic proximity Read ↗

Integration of miRNA‐regulatory networks in hepatic stellate cells identifies TIMP3 as a key factor in chronic liver diseaseSemantic proximity Read ↗

The miRNAs miR-211-5p and miR-204-5p modulate ER stress in human beta cellsSemantic proximity Read ↗

Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.Semantic proximity Read ↗

miRNA-101-1 and miRNA-221 expressions and their polymorphisms as biomarkers for early diagnosis of hepatocellular carcinoma.Semantic proximity Read ↗

Autophagy facilitates cytokine-induced ICAM-1 expression.Semantic proximity Read ↗

MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3Semantic proximity Read ↗

Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.