Article
Contribution of RING domain to retrovirus restriction by TRIM5alpha depends on combination of host and virus.
Virology - 10 Apr 2010
Maegawa Hikoichiro, Miyamoto Tadashi, Sakuragi Jun-Ichi, Shioda Tatsuo, Nakayama Emi E
Abstract excerpt
The anti-retroviral restriction factor TRIM5alpha contains the RING domain, which is frequently observed in E3 ubiquitin ligases. It was previously proposed that TRIM5alpha restricts human immunodeficiency virus type 1 (HIV-1) via proteasome-dependent and -independent pathways. Here we examined t...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
