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Article

Domain III of the envelope protein as a dengue vaccine target

28 Jan 2010

Abstract excerpt

A dengue vaccine should induce long-lasting, simultaneous protection to the four dengue viruses while avoiding the immune enhancement of viral infection. Domain III of the dengue envelope protein has been implicated in receptor binding, and is also the target of specific neutralizing antibodies. Domain III has emerged as a promising region for a subunit vaccine candidate. Here, we review the current state of...

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Identifiers

PMID: 20109025
DOI: 10.1586/erv.09.139

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