Article
A cytoskeleton-related gene, uso1, is required for intracellular protein transport in Saccharomyces cerevisiae.
The Journal of cell biology - 1 Apr 1991
Nakajima H, Hirata A, Ogawa Y, Yonehara T, Yoda K, Yamasaki M
Abstract excerpt
The Saccharomyces cerevisiae mutant strains blocked in the protein secretion pathway are not able to induce sexual aggregation. We have utilized the defect of aggregation to concentrate the secretion-deficient cells and identified a new gene which functions in the process of intracellular protein transport. The new mutant, uso1, is temperature sensitive for growth and protein secretion. At the restrictive...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Transport, Active
- Carrier Proteins
- Cloning, Molecular
- Cytoskeleton
- DNA, Fungal
- Electrophoresis, Polyacrylamide Gel
- Endoplasmic Reticulum
- Fungal Proteins