Article
Serum level of IGFBP3 and IGF1/IGFBP3 molar ratio in addition to PSA and single nucleotide polymorphism in PSA and CYP17 gene may contribute to early diagnostics of prostate cancer.
Neoplasma - 1 Jan 2010
Tajtakova M, Pidanicova A, Valansky L, Lachvac L, Nagy V, Sivonova M, Dobrota D, Kliment J, Petrovicova J
Abstract excerpt
The aim of the paper is to determine whether IGF1, IGFBP3 and IGF1/IGFBP3 molar ratio in addition to PSA and one-nucleotide polymorphism in PSA and CYP17 gene might contribute to early diagnostics of prostate cancer (PCa). Serum level of PSA, IGF1 and IGFBP3 in the group of 158 individuals (92 PCa and 66 controls) was examined by RIA method and IGF1/IGFBP3 was calculated. PCR RLFP method was used to examine one-...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.