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Article

Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET.

Journal of the American Chemical Society - 17 Feb 2010

Dicus Michelle M, Conlan Andrea, Nechushtai Rachel, Jennings Patricia A, Paddock Mark L, Britt R David, Stoll Stefan

Abstract excerpt

Human mitoNEET is a homodimeric iron-sulfur protein located in the outer mitochondrial membrane with unknown function, but which is known to interact with thiazolidinedione diabetes drugs. Each monomer houses a [2Fe-2S] cluster with an unusual (Cys)(3)(His)(1) ligation. The His ligand is importan...

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Identifiers

PMID: 20099820
DOI: 10.1021/ja909359g
PMCID: PMC2820139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20099820-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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