Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Label-free microarray imaging for direct detection of DNA hybridization and single-nucleotide mismatches.

Biosensors & bioelectronics - 15 Mar 2010

Ozkumur Emre, Ahn Sunmin, Yalçin Ayça, Lopez Carlos A, Cevik Elif, Irani Rostem J, DeLisi Charles, Chiari Marcella, Unlü M Selim

Abstract excerpt

A novel method is proposed for direct detection of DNA hybridization on microarrays. Optical interferometry is used for label-free sensing of biomolecular accumulation on glass surfaces, enabling dynamic detection of interactions. Capabilities of the presented method are demonstrated by high-throughput sensing of solid-phase hybridization of oligonucleotides. Hybridization of surface immobilized probes with 20...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Equipment Design

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Oligonucleotide Array Sequence Analysis

Share to Point Mutation

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Staining and Labeling

Source

Open in PubMed Open full text

Identifiers

PMID: 20097056
DOI: 10.1016/j.bios.2009.12.032
PMCID: PMC2824047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Label-free microarray imaging for direct detection of DNA hybridization and single-nucleotide mismatches.PMID 20097056Read ↗

High-throughput label-free detection of DNA hybridization and mismatch discrimination using interferometric reflectance imaging sensor.Semantic proximity Read ↗

Oligonucleotide-based label-free detection with optical microresonators: strategies and challenges.Semantic proximity Read ↗

DNA chips: state-of-the art.Semantic proximity Read ↗

Direct detection of DNA conformation in hybridization processes.Semantic proximity Read ↗

A review: fabrications, detections and applications of peptide nucleic acids (PNAs) microarray.Semantic proximity Read ↗

Optimizing the Toehold Strategy of On-Chip Nucleic Acid Hybridization Probe for the Discrimination of Single Nucleotide Polymorphism.Semantic proximity Read ↗

Preparation and use of metal surface-immobilized DNA hairpins for the detection of oligonucleotides.Semantic proximity Read ↗

Gold nanoparticle-based detection of genomic DNA targets on microarrays using a novel optical detection system.Semantic proximity Read ↗

Photonic crystals on copolymer film for label-free detection of DNA hybridization.Semantic proximity Read ↗

Zeptomole Biosensing of DNA with Flexible Selectivity Based on Acoustic Levitation of a Single Microsphere Binding Gold Nanoparticles by Hybridization.Semantic proximity Read ↗

Nano-graphene oxide as a novel platform for monitoring the effect of LNA modification on nucleic acid interactions.Semantic proximity Read ↗

Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.