Article
A 9-bp deletion homoplasmy in women with polycystic ovary syndrome revealed by mitochondrial genome-mutation screen.
Biochemical genetics - 1 Feb 2010
Zhuo Guangchao, Feng Guofang, Leng Jianhang, Yu Lin, Jiang Yan
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder presenting a challenge for clinical investigators. To investigate the association of a mitochondrial genetic basis with PCOS, we screened mutations of the whole mitochondrial genome in 57 women patients with PCOS and 38 healthy control individuals. Two-step PCR reactions were adopted to amplify and sequence the whole mitochondrial genome. A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.