Article
[Association of the C1858T polymorphism of the PTPN22 gene with type 1 diabetes].
Molekuliarnaia biologiia - 1 Jan 2000
Lavrikova E Iu, Nikitin A G, Seregin Iu A, Zil'berman L I, Tsitlidze N M, Kuraeva T L, Peterkova V A, Dedov I I, Nosikov V V
Abstract excerpt
To study the association with diabetes mellitus type 1 (T1DM) we performed TDT analysis and analysis of the distribution of frequencies of alleles and genotypes of polymorphic marker C1858T of the PTPN22 gene, encoding tyrosine phosphatase of non-receptor type (LYP). Groups of concordant (27 families) and discordant (62 families) sibpairs and groups of T1DM patients and unrelated controls of Russian origin were...
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