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Development and validation of a D-loop mtDNA SNP assay for the screening of specimens in forensic casework.

Forensic science international. Genetics - 1 May 2013

Chemale Gustavo, Paneto Greiciane Gaburro, Menezes Meiga Aurea Mendes, de Freitas Jorge Marcelo, Jacques Guilherme Silveira, Cicarelli Regina Maria Barretto, Fagundes Paulo Roberto

Abstract excerpt

Mitochondrial DNA (mtDNA) analysis is usually a last resort in routine forensic DNA casework. However, it has become a powerful tool for the analysis of highly degraded samples or samples containing too little or no nuclear DNA, such as old bones and hair shafts. The gold standard methodology still constitutes the direct sequencing of polymerase chain reaction (PCR) products or cloned amplicons from the HVS-1 and...

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PMID: 23510586
DOI: 10.1016/j.fsigen.2013.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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