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Article

Forensic mitochondrial coding region analysis for increased discrimination using pyrosequencing technology.

Forensic science international. Genetics - 1 Mar 2007

Andréasson Hanna, Nilsson Martina, Styrman Hanna, Pettersson Ulf, Allen Marie

Abstract excerpt

Analysis of mitochondrial DNA (mtDNA) is very useful when nuclear DNA analysis fails due to degradation or insufficient amounts of DNA in forensic analysis. However, mtDNA analysis has a lower discrimination power compared to what can be obtained by nuclear DNA (nDNA) analysis, potentially resulting in multiple individuals showing identical mtDNA types in the HVI/HVII region. In this study, the increase in...

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PMID: 19083726
DOI: 10.1016/j.fsigen.2006.10.002

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