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Development of a new screening method to determine the main 52 mitochondrial haplogroups through a single minisequencing reaction.

Mitochondrion - 1 Mar 2019

Palencia-Madrid Leire, Cardoso Sergio, Castro-Maestre Fernando, Baroja-Careaga Igor, Rocandio Ana M, de Pancorbo Marian M

Abstract excerpt

This work presents the design, development and optimization of a screening method based on single-base extension sequencing to simultaneously analyze a panel of 52 mitochondrial SNPs. This enables to recognize the main mitochondrial haplogroups and to discriminate even between lineages from the same phylogenetic branch that diverged in different continents. The unavailability of individuals harboring infrequent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29474835
DOI: 10.1016/j.mito.2018.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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