Article
Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function.
Cardiovascular research - 1 Jun 2010
Fritah Asmaà, Steel Jennifer H, Nichol Donna, Parker Nadeene, Williams Sharron, Price Anthony, Strauss Leena, Ryder Timothy A, Mobberley Margaret A, Poutanen Matti, Parker Malcolm, White Roger
Abstract excerpt
AIMS: Receptor-interacting protein 140 (RIP140) is a ligand-dependent cofactor for nuclear receptors that regulate networks of genes involved in cellular processes, including metabolism. An important role for RIP140 in metabolic control has been identified in RIP140 null mice, whose phenotypes in...
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