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Article

Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty.

The journal of nutrition, health & aging - 1 Jan 2010

Matteini A M, Walston J D, Bandeen-Roche K, Arking D E, Allen R H, Fried L P, Chakravarti A, Stabler S P, Fallin M D

Abstract excerpt

OBJECTIVE: This project was designed to follow-up prior evidence that demonstrated a significant association between vitamin B12 transport and metabolism and the frailty syndrome in community-dwelling older women. The cross-sectional relationship between genetic variants within six candidate genes along this pathway with serum methylmalonic acid (MMA) levels and frailty was evaluated in this same population of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20082058
DOI: 10.1007/s12603-010-0013-1
PMCID: PMC3042247

Genes

TCN2
MTHFR
MTR
MTRR
CBS
TCN1

Provenance

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Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty.PMID 20082058Read ↗

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