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Article

Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria.

Applied and environmental microbiology - 1 Mar 2010

Craig Jeffrey W, Chang Fang-Yuan, Kim Jeffrey H, Obiajulu Steven C, Brady Sean F

Abstract excerpt

The small-molecule biosynthetic diversity encoded within the genomes of uncultured bacteria is an attractive target for the discovery of natural products using functional metagenomics. Phenotypes commonly associated with the production of small molecules, such as antibiosis, altered pigmentation,...

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Identifiers

PMID: 20081001
DOI: 10.1128/AEM.02169-09
PMCID: PMC2832356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20081001-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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