Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A model for the clustered distribution of SNPs in the human genome.

Computational biology and chemistry - 1 Oct 2016

Lee Chang-Yong

Abstract excerpt

Motivated by a non-random but clustered distribution of SNPs, we introduce a phenomenological model to account for the clustering properties of SNPs in the human genome. The phenomenological model is based on a preferential mutation to the closer proximity of existing SNPs. With the Hapmap SNP data, we empirically demonstrate that the preferential model is better for illustrating the clustered distribution of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, X
Share to Genome, Human
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Theoretical

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 27318295
DOI: 10.1016/j.compbiolchem.2016.06.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A model for the clustered distribution of SNPs in the human genome.PMID 27318295Read ↗

Even small SNP clusters are non-randomly distributed: is this evidence of mutational non-independence?Semantic proximity Read ↗

Distribution of human single-nucleotide polymorphisms is approximated by the power law and represents a fractal structure.Semantic proximity Read ↗

Association testing of clustered rare causal variants in case-control studies.Semantic proximity Read ↗

Locating suspicious lethal genes by abnormal distributions of SNP patternsSemantic proximity Read ↗

Detecting SNP combinations discriminating human populations from HapMap data.Semantic proximity Read ↗

SNPs as Stochastic Oscillators in Inheritance of Human Diseases.Semantic proximity Read ↗

Genome-wide association studies using haplotype clustering with a new haplotype similarity.Semantic proximity Read ↗

Characterizing Fractal Genetic Variation in the Human Genome from the Hapmap Project.Semantic proximity Read ↗

Distribution of human SNPs and its effect on high-throughput genotyping.Semantic proximity Read ↗

Why are GWASs limp about the X chromosome?Semantic proximity Read ↗

A Note on the Relations Between Spatio-Genetic Models.Semantic proximity Read ↗

SNP uniqueness problem: a proof-of-principle in HapMap SNPs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.