Article
Testing of chromosomal clumping of gene properties.
Statistical applications in genetics and molecular biology - 1 Jan 2009
Fernandez-Ricaud Luciano, Dalevi Daniel, Blomberg Anders, Nerman Olle
Abstract excerpt
Clumping of gene properties like expression or mutant phenotypes along chromosomes is commonly detected using completely random null-models where their location is equally likely across the chromosomes. Interpretation of statistical tests based on these assumptions may be misleading if dependencies exist that are unequal between chromosomes or in different chromosomal parts. One such regional dependency is the...
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