Article
Importance of age of onset in pancreatic cancer kindreds.
Journal of the National Cancer Institute - 20 Jan 2010
Brune Kieran A, Lau Bryan, Palmisano Emily, Canto Marcia, Goggins Michael G, Hruban Ralph H, Klein Alison P
Abstract excerpt
BACKGROUND: Young-onset cancer is a hallmark of many familial cancer syndromes, yet the implications of young-onset disease in predicting risk of pancreatic cancer among familial pancreatic cancer (FPC) kindred members remain unclear. METHODS: To understand the relationship between age at onset of pancreatic cancer and risk of pancreatic cancer in kindred members, we compared the observed incidence of pancreatic...
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