Article
Natural variability of in vitro adherence to fibrinogen and fibronectin does not correlate with in vivo infectivity of Staphylococcus aureus.
Infection and immunity - 1 Apr 2010
Ythier Mathilde, Entenza Jose M, Bille Jacques, Vandenesch François, Bes Michèle, Moreillon Philippe, Sakwinska Olga
Abstract excerpt
Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set out to determine the range of adherence phenotypes in carriage isolates of S. aureus, to compare...
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