Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis.

doi:10.1128/iai.63.12.4738-4743.1995

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Article

Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis.

Infection and immunity - 1 Dec 1995

Moreillon P, Entenza J M, Francioli P, McDevitt D, Foster T J, François P, Vaudaux P

Abstract excerpt

The pathogenic role of staphylococcal coagulase and clumping factor was investigated in the rat model of endocarditis. The coagulase-producing and clumping factor-producing parent strain Staphylococcus aureus Newman and a series of mutants defective in either coagulase, clumping factor, or both w...

Topics

Animals
Bacterial Adhesion
Coagulase
Endocarditis, Bacterial
Female
Mutation
Rats
Rats, Wistar
Staphylococcal Infections

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