Article
Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis.
Infection and immunity - 1 Dec 1995
Moreillon P, Entenza J M, Francioli P, McDevitt D, Foster T J, François P, Vaudaux P
Abstract excerpt
The pathogenic role of staphylococcal coagulase and clumping factor was investigated in the rat model of endocarditis. The coagulase-producing and clumping factor-producing parent strain Staphylococcus aureus Newman and a series of mutants defective in either coagulase, clumping factor, or both were tested for their ability (i) to attach in vitro to either rat fibrinogen or platelet-fibrin clots and (ii) to...
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